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16 August, 10:25

Wich phase of the cell cycle is most affected by cytarabine

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  1. 16 August, 11:22
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    Its mode of action is due to its rapid conversion into cytosine arabinoside triphosphate, which damages DNA when the cell cycle holds in the S phase (synthesis of DNA). Rapidly dividing cells, which require DNA replication for mitosis, are therefore most affected.
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