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1 June, 17:37

g Using these types of genetic changes: Base substitution Transition Transversion Missense mutation Nonsense mutation Insertion Deletion Frameshift mutation Label these genetic changes (a-e). More than one answer may apply to each answer. a. GC->CG in the protein coding region on a gene. b. GC->TA in a GAA glutamate codon c. Loss of three bases GAA for a glutamate codon d. GC->CG in a tRNA gene e. GC->AT in the ribsome binding site of a mRNA

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  1. 1 June, 18:41
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    a. GC->CG in the protein coding region on a gene. - Base substitution

    b. GC->TA in a GAA glutamate codon - Base substitution

    c. Loss of three bases GAA for a glutamate codon - Deletion

    d. GC->CG in a tRNA gene - Insertion

    e. GC->AT in the ribsome binding site of a mRNA - Frameshift mutation

    Explanation:

    DNA mutation occurs as a result of a change in the gene sequence of the protein being coded by the genes. Several causes of mutation involve radiation, heavy metal exposure, etc. There are different types of gene mutation. These include a deletion where the bases are deleted. Another one is the insertion where a base is inserted into the sequence. This lengthens the base sequence of the gene. Another mutation is the base mutation - this can take place as a result of inversion. Inversion reverses the order of the bases in a sequence like this: normal CGGA → AGGC

    These mutations result in disorder e'g Downs syndrome, Puckingtons disease, Cystic fibrosis etc.
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