Ask Question
8 March, 21:00

TP53 is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cancer than those without the recessive gene?

+1
Answers (1)
  1. 8 March, 23:54
    0
    Since it is a recessive gene, tumor suppressor genes required the inactivation of both alleles, this is usually accomplished by the mutation of one allele and a targeted homozygous deletion of the second allele. This leads to an effective inactivation of the suppressor genes with the mutations acting a a dominant negatives. This way, patients are put at a higher risk of developing cancer
Know the Answer?
Not Sure About the Answer?
Find an answer to your question ✅ “TP53 is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive ...” in 📘 Biology if you're in doubt about the correctness of the answers or there's no answer, then try to use the smart search and find answers to the similar questions.
Search for Other Answers