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20 January, 11:47

In humans, the allele for hemophilia, h, is recessive. which is true of a woman with the genotype xhxh? a. the woman and all of her children are hemophiliacs. b. all of her sons will inherit the allele for hemophilia. c. she is a carrier of hemophilia but does not have the condition.

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  1. 20 January, 14:38
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    The answer is b. all of her sons will inherit the allele for hemophilia.

    Hemophilia is X-linked recessive disorder. It is known that there are two X chromosomes (one from a mother and one from a father) in females and one X chromosome (from the mother) and one Y chromosomes (from the father) in males. In females, X-linked recessive disorder has the same pattern of inheritance as an autosomal recessive disorder.

    So, if xh is recessive and xH is dominant allele, a mother which has xhxh genotype has the condition (so, c is not the right answer). Further, if a father has no condition, thus his genotype is xHy, their daughters will be carriers but without the condition (so, the choice a could be right only if we know that the father has hemophilia too (xhy). Therefore, since the mother (xhxh) will give her x chromosome to her sons, they will all inherit the allele for hemophilia, and choice b. is the right answer.
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