The body's most important nonspecific defense against pathogens is/are

A. tears.

B. mucus.

C. saliva.

D. skin.

Skin because it shields the body from almost everything

The body's most important nonspecific defense against pathogens is the skin. The nonspecific defense system in the body guards against keeping infections from the body. Some of the nonspecific defenses are tears, mucus, and sweat among others. The correct answer will be D.