What is the correct order of a signal being transmitted across a neuromuscular junction?

Arrival of end plate potential-acetylcholine release-action potential-binding of acetylcholinesterase to its substrate

Arrival of action potential-acetylcholine release-end plate potential-binding of acetylcholinesterase to its substrate

Acetylcholine release-arrival of action potential-end plate potential-binding of acetylcholinesterase to its substrate

Binding of acetylcholinesterase to its substrate-acetylcholine release-arrival of action potential-end plate potential

Question

Biology

Diego Meadows

18 November, 21:59

What is the correct order of a signal being transmitted across a neuromuscular junction?

Arrival of end plate potential-acetylcholine release-action potential-binding of acetylcholinesterase to its substrate

Arrival of action potential-acetylcholine release-end plate potential-binding of acetylcholinesterase to its substrate

Acetylcholine release-arrival of action potential-end plate potential-binding of acetylcholinesterase to its substrate

Binding of acetylcholinesterase to its substrate-acetylcholine release-arrival of action potential-end plate potential

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Porter Leach · Answer 1

Arrival of action potential-acetylcholine release-end plate potential-binding of acetylcholinesterase to its substrate

Only one action potential arrives at the neuromuscular junction, is the synapse stimulated. Once action potential arrives, it causes release of acetylcholine into synaptic cleft. After this, the relevant potential is transmitted to motor end. Since function of acetylcholine is completed, acetylcholine is degraded by acetylcholinesterase.