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8 April, 16:44

Remember that the glomerulus is the initial filtering sieve of the nephron.

Know that the glomerular filtration rate (GFR) for all of the nephrons in both kidneys is approximately 125mL per minute. That means that about 125mL of fluid and dissolved substances are filtered out of the blood per minute. The fluid moves into the Bowman's capsule, the first collecting tube of the nephron. Use this information to complete the calculations and answer the questions below.

o Calculate the GFR per day. Show your work. Express your answer in liters (L) per day.

o About how many 2L soda bottles would you fill per day?

o What do you think about this value? Do you produce this much urine in one day? What must be happening to some of the fluid that is being filtered by the glomerulus?

o If the first part of nephron action is called filtration, what name do you think is given to the second part of the process, where precious water is returned back into the blood?

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  1. 8 April, 20:35
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    Filtration rate = 125 mL/minute = 0.125 L/min

    Minutes in a day = 24 hours x 60 minutes per hour

    Minutes in a day = 1440

    Total filtrate per day = 0.125 x 1440 = 180 L

    Number of 2 L bottles to be filled = 180 / 2

    = 90 bottles

    This value is very large and we do not produce this much urine in a day. This means a portion of the fluid is being reabsorbed.

    Absorption.
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