What will happen to a blood cell that is placed in a solution with a greater concentration of solutes?

Eventually the increase in water may cause the blood cells to burst (cytolysis.) In a hypertonic solution, the concentration of dissolved solutes is greater than that of the cell ... If the salt solution outside is 20% salt, then the water concentration is 80%. The red blood cells will shrink in size due to osmotic-like pressure differences until it reaches a "favorable" size.