What a three of the signs of an allergic reaction to iv t-pa?

Look out for angioedema (like hives but a deeper swelling due to an allergic reacrion), bleeding (such as intracranial, gastrointestinal and genitourinal hemorrhaging) and adverse reactions to drugs. Nausea, blood pressure spikes, severe headaches, acute hypertsnsion, etc are other signs of negative reacrions to iv t-pa as well.