The terms motif (fold) and domain describe levels of protein organization more complicated than primary or secondary structure. Differentiate between motifs and domains by moving each phrase to the appropriate bin. Note: If you answer any part of this question incorrectly, a single red X will appear indicating that one or more of the phrases are sorted incorrectly.

Motifs Domain Both

Choices are:

Stabilized by hydrophobic interactions

Stable globular units

depends on primary structure

clusters of seconday structure

Beta Alpha Beta unit

may be distinct functional units in a protein

unit of tertiary structure

repetetive supersecondary structure

may retain a 3D structure when seperated from rest of the protein

Each specific property of motif and domain is explained.

Explanation:

Domain;

May retain a 3D structure when separated from rest of the protein. Unit of tertiary structure because alpha helix and beta sheets are units of secondary structure. Stable globular units like pyruvate kinase May be distinct functional units in a protein

Motif;

Repetetive supersecondary structure because they contain cluster of secondary structure. Beta Alpha Beta unit is an example of motif Clusters of secondary structure

Both Motif and Domain;

Stabilized by hydrophobic interactions like hydrogen bonding stabilize the both. Depends on primary structure like the arrangement of amino acid in polypeptide chain determine the secondary and tertiary structure of proteins.