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9 November, 08:47

What is the product of the reaction of an alcohol and a carboxylic acid when heated together

under acidic conditions?

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  1. 9 November, 10:47
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    The direct reaction of a carboxylic acid with an amine would be expected to be difficult because the basic amine would deprotonate the carboxylic acid to form a highly unreactive carboxylate. However when the ammonium carboxylate salt is heated to a temperature above 100 C water is driven off and an amide is formed.
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