hich of the followings decrease the affinity of adult Hb with O2? A. 2,3 BPG B. hydrogen ion C. CO2 D. Ferrous ion

A. 2,3 BPG

Explanation:

2,3-bisphosphoglycerate (BPG), otherwise known as 2,3-DPG, enables the transition of hemoglobin from a very high-oxygen-affinity state to a reduced-oxygen-affinity state.

Tissues hemoglobin oxygen affinity is reduced by numerous physiological factors including.

1. Temperature Increased,

2. Carbon dioxide,

3. Acid and

4. 2,3-Bisphosphoglycerate (2,3-BPG)

all of which can contribute to decrease the oxygen affinity of hemoglobin which favours unloading and increased oxygen availability to our body cells.