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ChemistryChemistry
17 March, 00:09

A deficiency in thiamine (TPP) will directly decrease the activity of which of the following enzymes? a. Pyruvate carboxylase b. Glucose 6-phosphate dehydrogenase c. Aldolase Bd. Transketolase

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  1. 17 March, 04:05
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    d. Transketolase

    Explanation:

    Transketolase utilize thiamine diphosphate (ThDP) as cofactor has reduced activity during the thiamine deficiency and results in the tissue damage. The levels of steady-state mRNA of transketolase in human lymphoblasts, fibroblasts and neuroblastoma cells are found to be lower in the thiamine-deficient cultures.

    Thus, deficiency in TPP directly decrease the activity of enzyme, transketolase.
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Home » Chemistry » A deficiency in thiamine (TPP) will directly decrease the activity of which of the following enzymes? a. Pyruvate carboxylase b. Glucose 6-phosphate dehydrogenase c. Aldolase Bd. Transketolase
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