How do the HOX genes in the paddlefish match the HOX genes in human

Hox are transcription factors that are evolutionarily conserved across bilaterians and, therefore, they share sequence homology between paddlefish and humans.

Explanation:

The Hox genes represent a family of homeodomain transcription factors that play roles in the development of the axial and appendicular skeleton, being therefore critical during embryonic development. In this case, the human Hox genes are homologous to homeobox genes found in the paddlefish. These genes have a DNA-binding domain of 60 amino acids which is evolutionarily conserved in bilaterian species including paddlefish and human species.