What factors isolate the individual?

There are many factors that isolate the individual. The social isolation is the complete lack of contact between an individual and the rest of the society. One of the main factors is staying at home for lengthy periods of time, having no communication with family or friends, and in fact avoiding these contacts when the possibility do arise.

It is dangerous because it can be a chronic condition that affects all aspects of a person's existence and can lead to feelings of loneliness, fear of others, social panic or negative self esteem.

The lack of contact with other beings can also lead to depression. We, humans, are naturally social beings and need to have contact with other to have a healthy, mindful life.