What factors are most responsible for significant changes in the climate

The Factors are most responsible for significant changes in the climate are discussed below.

Explanation:

Many agents, both natural and human, can produce variations in Earth's power scale, including Changes in the sun's power approaching Earth. Variations in the thoughtful of Earth's environment and exterior. Variations in the greenhouse impact, which influences the quantity of energy preserved by the Earth's climate. The range from the equator influences the environment of a site.

the conventional belief would be us but if you look at a graph of temp change you will find were simply at a low, the answer would be distance from sun and other things.