For which of the following major world events was the spread of diseases a

negative effect?

A the technological revolution

B the mapping of the European world

C the Columbian Exchange

D the Reformation

C

Explanation:

They all were technically, but that makes the most sense

Option C.

Explanation:

The Columbian Exchange, is the right answer.

The Columbus exchange had some positive and some negative effects, positive for Europe, as it increased the food supply, negative for the people of the New World, as they came into contact with catastrophic diseases, Smallpox was one such. Some other diseases that affected among the native people include measles, influenza, smallpox and typhus fever etc. This contact during the first hundred years of Columbian exchange trapped Americans in a virtual web of new diseases. The Native Americans had no prior resistance to these diseases, was the chief cause of the massive depopulation of the Native Americans. The newly established oceanic slave trade of 1518, added a new burden of disease from Africa on the Native American population. The influence of European epidemics and military victory was so profound and unexpected that other patterns of viable development were abruptly modified