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The term Mesopotamia refers to land between

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Sumer and Egypt

Uruk and Ur

the Arabian peninsula and the Sinai peninsula

the Tigris and Euphrates rivers

the Tigris and Euphrates rivers

Explanation:

Mesopotamia was a very fertile and good area located around and between the two rivers Tigris and Euphrates. The first civilization rose here and many developments and settlements were made. Many technological breakthroughs were made in this area and small towns developed. New agriculture and watering methods were implemented which led to population increase.