Who were the mesopotamian and what did they do?

Mesopotamia is a region of southwest Asia in the Tigris and Euphrates river system that benefitted from the area's climate and geography to host the beginnings of human civilization. Its history is marked by many important inventions that changed the world, including the concept of time, math, the wheel, sailboats, maps and writing. Mesopotamia is also defined by a changing succession of ruling bodies from different areas and cities that seized control over a period of thousands of years.