How did disease have a greater impact on the native cultures of the New World than war or commerce?

Answer: The Europeans brought sicknesses and diseases from Europe to the New World and it devastated countless Native American cultures and tribes because their bodies weren't prone to the diseases like the Europeans were. It was natural bio weaponry. The Europeans also tried to make the Native Americans into slaves, but their immune systems weren't strong, so They died. This lead to the Europeans bringing in African Americans as slaves.