What problems faced Maryland and Virginia?

One of the problems the people of Maryland faced was religious prejudice. Lot of people who immigrated to Maryland were Catholic but most people in the colonies were not Catholic, so there was a some amount of harassment. Border disputes, class warfares, Apostate native Americans, runaway servants and slaves were other problems faced by Maryland people around 1609.

Cash crops were grown in Virginia and Maryland but because of greed of cash, it caused them to attack on Native Americans and grab their land.