John C. Fremont was the first Republican Presidential candidate to win the office in 1856

False.

Explanation:

I'm assuming by the syntax that this is a true or false question.

John C. Fremont was the first Republican Presidential candidate and he did run in 1856, but he did not win. Fremont, in fact, was never elected President. James Buchanan, the Democratic nominee, defeated Fremont in 1856.

The first Republican President was Abraham Lincoln, inaugurated only five years later in 1861.

False I think is the answer