The earliest disputes in the United States government could ber traced to

I believe the answer is: C) Geographic differences

For example, slavery issues between states. The industrial revolution which originated in England come first to united states through the northern states because they are geographically closer.

This made the use of slaves for labour seems necessary by business owners in northern states which influence the number of support that people in northern states have to eliminate slavery.

When the government was already established then the earliest disputes were mostly about trading rights between states and between foreign powers and the United States. Before it was fully formed the main disputes were the ratification of the constitution and establishing rights.