What happened to American Indians after 1492? A-They began growing tea and coffee. B-Most perished from disease. C-Their population decreased by nearly twenty percent. D-They began selling horses for gold.

The American Indians were nearly wiped out following the discovery of both Americas. So the answer that would be correct in this case would be C - Their population decreased by nearly twenty percent. We really have to consider how many people actually died here if we know that around 20 % of all the population of those areas died.