Did the Black Death have any effect on Humanism? If so, what effect?

The Black Death, more commonly referred to or known as 'The Black Plague', killed at least 25 million people from 1347 to 1352. When the disease seemed to be relinquished many were highly devastated. Most came to the conclusion of God being exasperated with mankind, or thinking that there was no God at all. Churches greatly endeavored putting a stop to the Ebony Death by continuously praying to God, in hopes of receiving a a resolution. When prayers seemed to go unanswered many grew weary with faith and came to the conclusion that religion was no longer valid. Consequently, the people sought out their own remedy, to avail their own cure to this fatal sickness.