In what ways did the relationship between whites and Indians (Powhatans) in Virginia establish the pattern for later white-Indian relations across North America? ... ?

The relationship or encounter between the whites and the Indians in Virginia went well at first. This established many of the patterns that characterized later Indian-white relations in North America, including disease, warfare, and removal. Indian societies undertook their own major changes due to disease, trade, and warfare. For a time after the Atlantic coastal tribes were nearly wiped out, the larger Indian peoples of the Appalachian area created a forbidding barrier to white expansion.