Probability with Huntington's disease?

Huntington disease is a rare degenerative human disease determined by a dominant allele, HD. The disorder is usually manifested after the age of 45. A young man has learned that his father has developed the disease; his mother does not have the disease (and does not carry to HD disease allele).

What is the probability that the young man will later develop the disease?

If the young man has a child with a woman who does not carry the HD disease allele, what is the probability that their first child will be affected by Huntington disease as ... ?

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Mathematics

Babykins

6 September, 18:12

Probability with Huntington's disease?

Huntington disease is a rare degenerative human disease determined by a dominant allele, HD. The disorder is usually manifested after the age of 45. A young man has learned that his father has developed the disease; his mother does not have the disease (and does not carry to HD disease allele).

What is the probability that the young man will later develop the disease?

If the young man has a child with a woman who does not carry the HD disease allele, what is the probability that their first child will be affected by Huntington disease as ... ?

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Bria Gonzalez · Answer 1

For the answer to the question above.

There is already an answer inside the question.

"You're correct that the man has a 50% probability of carrying the Huntington's allele. Now, if he does have it, the probability that his first child will also inherit the Huntington's allele is also 50%.

But there is only a 50% chance that the man has it to give to his son. So:.5 X. 5 = 0.25 = 25% There is a 25% chance that the man's first child will be affected by Huntington's disease."