Which weather event is capable of destroying homes and uprooting trees due to a low pressure area at its center

You're talking about a tornado.

It's not so much the low pressure that's so dangerous in the center of a tornado. It's more a matter of the high winds that are caused by the low pressure.

Answer: Tornado

Explanation:

A tornado is a type of wind storm which exhibit a tall funnel shaped column of air. The air spins round very fast in tornado and causes a lot of damage. The powerful wind column makes a wind spiral possibly around a center exhibiting a low atmospheric pressure. These storms are also called as twisters. The objects, trees, buildings and human beings which come in contact with the tornado get affected and destroyed.