Marissa suffers from panic disorder, where she experiences unpredictable, unbearable episodes of panic that closely resemble the symptoms of a heart attack. what criterion for defining abnormality does this description of her disorder represent?

The answer is "personal distress".

Personal distress is an aversive, self-centered passionate response to the worry or appreciation of another's enthusiastic state or condition. This negative full of feeling state frequently happens because of passionate virus when there is perplexity amongst self and other.