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11 April, 12:57

NBAC specifically states a person may be vulnerable "because they have difficulty providing voluntary, informed consent arising from limitations in decision-making capacity ... or situational circumstances ..., or because they are especially at risk for exploitation" While high potential for individual benefit from participating in research might increase the likelihood that a person might participate despite high risks, the root cause of their vulnerability is the potential for exploitation.

Next, the NBAC looked at characteristics individuals might have that would prevent them from being able to provide voluntary informed consent. The traits may be thought of as falling into six broad areas: cognitive or communicative, institutional, deferential, medical, economic, and social.

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  1. 11 April, 16:20
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    Answer: NBAC proposed a concept of vulnerability in research based on features of potential subjects or of their situation

    Explanation: The National Bioethics

    Advisory Committee sees vulnerable subjects as persons who "have difficulty providing voluntary, informed consent

    arising from limitations in decision-making capacity, or situational circumstances ...

    or because they are especially at risk for exploitation."

    Many of the regulations and discussions in bioethics that surround protecting human

    subjects in research are reactions to cases seen as unethical research

    practices. Many of these cases involved mistreatment of individuals or groups of

    individuals now referred to as vulnerable populations, or populations requiring

    additional considerations and/or protections.
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