1. Edgar Allan Poe is believed to have had delirium in the last days of life. Today, what is the recommended first line of treatment for people with delirium?

For the individuals who suffer from delirium that first line of treatment includes non-pharmacological strategies.

Explanation:

After the underlying cause of the delirium is identified, the series of non-pharmacological interventions should be performed.

In particular, they include, optimizing hydration and nutrition supply. If deemed necessary, oxygen and electrolytes level should also be managed. The individual has to be set in a comfortable environment, with optimized lighting and noise reduction that promote healthy sleep-wake cycle, and offered a company of friends and family members who can calm him or her and provide reassurance.