The second amendment wouldmost likely prevent the federal government from passing which law? (APEX)

The answer is: a law preventing Americans from carrying concealed handguns.

The Second Amendment of the United States Constitution protects people's right to keep and bear arms, and to use arms as self-defense within their property. Therefore, the federal government would not be able to pass a law which prevents people from carrying handguns (such an action would be considered unconstitutional).