What was the underlying factor behind the Nullification Crisis?

"Nullification Crisis of 1832 centered around Southern protests against the series of protective tariffs (taxes) that had been introduced to tax all foreign goods in order to boost the sales of US products and protect manufacturers in the North from cheap British goods. The South, being predominantly agricultural, and reliant on the North and foreign countries for manufactured goods, saw the protective tariffs as severely damaging to their economy. During the administration of John Quincy Adams his Vice President, John C. Calhoun, had drafted the South Carolina Exposition, a document that declared the tariffs were unconstitutional that caused the Nullification Crisis bringing the sectional interests of the North and the South into open conflict for the first time."