Sickle cell disease results from an amino acid change from Valentine to glutamic acid. The result of this amino acid change is a deformed hemoglobin protein that does not carry oxygen well. What type of genetic mutation caused the amino acid change in a person with sickle cell anemia?

a. frameshift mutation

b. silent mutation

c. nonsense mutation

d. missense mutation

Question

Biology

Krish

11 July, 01:41

Sickle cell disease results from an amino acid change from Valentine to glutamic acid. The result of this amino acid change is a deformed hemoglobin protein that does not carry oxygen well. What type of genetic mutation caused the amino acid change in a person with sickle cell anemia?

a. frameshift mutation

b. silent mutation

c. nonsense mutation

d. missense mutation

+3

Answers (1)

Know the Answer?

Hadley Nolan · Answer 1

D. Missense mutation.

A - the whole protein would be off, not just one AA

B - the disease wouldn’t occur

C - nonsense would end up in a truncated protein ((so shorter protein)