1 - What does mRNA do after it transcribes the instructions from DNA?

2 - During Translation, how does mRNA match up with tRNA?

1. Leaves the nucleus and enters the cytoplasm to become translated into a protein

2. tRNAs possess anticodons that recognise codons on the mRNA sequence

Explanation:

1. After transcription, the primary mRNA transcript is processed into a mature mRNA. This mature mRNA then leaves the nucleus and enters the cytoplasm where it binds to organelles called ribosomes.

Ribosomes are the site of protein synthesis. It is here that the mRNA is translated into a protein sequence through the actions of specialized RNAs called tRNAs. tRNAs use the mRNA sequence to bring the appropriate sequence of amino acids to the ribosome. Amino acids are linked up in a chain to form a polypeptide sequence, which becomes a protein.

2. The tRNAs are able to bring the correct amino acids to the ribosome because they "read" the sequence of the mRNA. They do this by recognising triplet sequences called codons. That is, recognises 3 bases on an mRNA sequence. It does this because tRNAs possess anticodons that are complementary to the codon. Each codon specifies for a specific tRNA, which brings the specific amino acid. It is in this way that the mRNA sequence dictates the protein sequence.