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21 October, 09:49

A new compound forms permanent crosslinks between the two strands of DNA in a chromosome. How can it function in chemotherapy against cancer? A. It would block DNA replication B. it would block spindle formation C. it would prevent chromosome condensation

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  1. 21 October, 10:28
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    A. It would block DNA replication

    Explanation:

    The first step in DNA replication is the break of the DNA double helix. The break allows the DNA polymerase to bind to the single DNA strand and perform the synthesis of the complementary strand. Errors may occur in the process of DNA replication that affect the organism.

    B) it IS NOT true because the formation of the spindle is a different independent process, and occurs in the presence of chromosomes with crosslinked strands.

    C) it IS NOT true because condensation of the chromosomes occurs when teir DNA strands are crosslinked.
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