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2 June, 08:03

If A/A ⋅ B/B is crossed with a/a ⋅ b/b and the F1 is testcrossed, what percentage of the testcross progeny will be a/a ⋅ b/b if the two genes are (a) unlinked; (b) completely linked (no crossing over at all); (c) 10 m. u. apart; (d) 24 m. u. apart?

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  1. 2 June, 11:47
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    a) 25%; b) 50%; c) 45%; d) 38%

    Explanation:

    a) Unlinked genes

    A/A B/B X a/a b/b

    F1: A/a B/b

    Testcross A/a B/b X a/a b/b

    The homozygous recessive individual only produces ab gametes.

    The F1 produces four types of gametes (each of them with a frequency of 1/4) : AB, Ab, aB and ab.

    25% of the progeny will be a/a b/b.

    b) Completely linked genes

    AB/AB X ab/ab

    F1: AB/ab

    Testcross AB/ab X ab/ab

    The F1 produces only two types of gametes, the parentals (each of them with a frequency of 1/2) : AB and ab.

    50% of the progeny will be ab/ab.

    c) 10 m. u. apart

    AB/AB X ab/ab

    F1: AB/ab

    Testcross AB/ab X ab/ab

    The F1 produces four types of gametes, the parentals AB and ab and the recombinants Ab and aB.

    Since the genes are 10mu apart, 10% of the produced gametes will be recombinant and 90% will be parentals. Since there are two types of parental gametes, each of them has a frequency of 45%.

    45% of the progeny will be ab/ab.

    d) 24 m. u. apart

    This is very similar to c).

    Since the genes are 24mu apart, 24% of the produced gametes will be recombinant and 76% will be parentals. Since there are two types of parental gametes, each of them has a frequency of 38%.

    38% of the progeny will be ab/ab.
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