The histamine H1 receptor is one of several existing histamine G protein-coupled receptors. Depending on many factors, including the type of receptor, histamine can trigger a variety of responses, including vasodilation, smooth muscle contraction, stimulation of gastric secretion, cardiac stimulation, and increased vascular permeability (causing runny nose and watery eyes). Which of the following could account for the different cellular responses to histamine?

Select all that apply.

a. the types of relay molecules within the cell

b. the enzyme that is activated by the G protein associated with the receptor

c. the type of second messengers involved in the signal transduction pathway

d. the cell type in which the histamine receptor is located

e. the type of signaling molecule

the cell type in which the histamine receptor is located the type of second messengers involved in the signal transduction pathway the types of relay molecules within the cell the enzyme that is activated by the G protein associated with the receptor

Explanation:

Histamine is a molecule that fulfills a dual function of communication in our body. Depending on where you are, it can act as both a hormone and a neurotransmitter. Therefore, its function is to regulate some of our biological functions. In addition, it allows certain cells to transmit information between them.

On the other hand, it plays a key role in regulating the immune system. It also regulates digestive system functions such as the creation of gastric acid in the stomach. It also plays an essential role in regulating our vital rhythms.

This variety of histamine functions occurs due to the type of cell in which the histamine receptor is located, the type of second messengers involved in the signal transduction pathway, the enzyme that is activated by the receptor-associated G protein, and the types of relay molecules within the cell.