Cancer cells exhibit a variety of differences from normal cells in cell adhesion, cell junctions, and cell effects on the extracellular matrix, some of which facilitate metastasis. Explain three changes found in some cancer cells related to these aspects of cell structure and function.

In cancer, cells loss their adhesion because protein expression involved in this process is dysregulated

Studies suggest that cell junctions are critical for cancer progression and metastasis

Finally, cancer cells modify the extracellular matrix since this matrix may act as a barrier for the migration of cancer cells