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23 September, 15:40

If you observe rod-shaped red cells after the Gram stain, you can assume their cell walls contain endotoxin. True or false?

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  1. 23 September, 18:32
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    The right answer is True.

    Endotoxins are lipopolysaccharide (LPS) and thermostable toxins.

    Endotoxins are found on the outer surface of the outer membrane of Gram (-) bacteria. Elless are released following the lysis of the bacteria. This can occur during sepsis with G (-) bacilli treated massively with antibiotics.

    *Endotoxins are lipidic in nature. They correspond to lipid A of LPS. This confers on them properties characteristic of lipids: - They are not very sensitive to heat. They can not be inactivated by heating.

    *They are not very immunogenic: There is almost no antibody produced against endotoxins. We can not conceive of vaccines against them.
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