When researchers conduct experiments on humans, what three important issues do they have to take into consideration?

Respect for persons

'Respect for persons incorporates at least two ethical convictions: first, that individuals should be treated as autonomous agents, and second, that persons with diminished autonomy are entitled to protection.'

Beneficence

'Two general rules have been formulated as complementary expressions of beneficent actions in this sense: (1) do not harm and (2) maximize possible benefits and minimize possible harms.'

Justice

'An injustice occurs when some benefit to which a person is entitled is denied without good reason or when some burden is imposed unduly ... For example, the selection of research subjects needs to be scrutinized in order to determine whether some classes (e. g., welfare patients, particular racial and ethnic minorities, or persons confined to institutions) are being systematically selected simply because of their easy availability, their compromised position, or their manipulability, rather than for reasons directly related to the problem being studied. Finally, whenever research supported by public funds leads to the development of therapeutic devices and procedures, justice demands both that these not provide advantages only to those who can afford them and that such research should not unduly involve persons from groups unlikely to be among the beneficiaries of subsequent applications of the research.'