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22 May, 11:02

The structure of aba is shown below. why was this a suitable substitution for a cys residue? under what circumstances would it not be suitable?

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  1. 22 May, 14:56
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    Answer and explanation;

    -Aba is a suitable replacement because Aba and Cys have approximately the same sized side chain and are similarly hydrophobic.

    -However, Aba cannot form disulfide bonds so it will not be a suitable replacement if these are required.

    -Alpha-Aminobutyric acid is biosynthesized by transaminating oxobutyrate, a metabolite in isoleucine biosynthesis.
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