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22 November, 04:16

Which genotype for the sickle cell anemia trait is associated higher survival rates in areas where malaria is prevalent?

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  1. 22 November, 06:46
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    Answer: Sickle hemoglobin (HbS) allele

    Explanation:

    Individuals with sickle cell alleles have an evolutionary benefit because they can survive malaria. The sickle cell mutation is a type error in the gene's DNA code, which tells the body how to produce a form of haemoglobin (Hb), (the oxygen-carrying molecule in our blood) which is called Sickle hemoglobin (HbS) allele.

    Sickle hemoglobin (HbS) allele carriers have traits that makes a person resistant to malaria. Red blood cells of anemic person contains some abnormal hemoglobin which to sickle when they are infected by the malaria parasite. The infected cell then pass via spleen, which seperates them out because of the sickle shape and along with them malarial bacteria is also removed.

    Hence, the correct genotype is Sickle hemoglobin (HbS) allele.
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